| Brandon Saad, TOM | LW/RW | October 27, 1992 | Pittsburgh, Pennsylvania, United States |
| Aleksi Saarela, PHI | C | January 7, 1997 | Helsinki, Finland |
| Santeri Saari, CGY | D | October 18, 1994 | Helsinki, Finland |
| Vili Saarijarvi, STL | D | May 15, 1997 | Rovaniemi, Finland |
| Scott Sabourin, HBG | RW | July 30, 1992 | Orleans, Ontario, Canada |
| Jack Sadek, LON | D | April 19, 1997 | Lakeville, United States |
| Dylan Sadowy, DUB | LW | April 2, 1996 | Brampton, Ontario, Canada |
| Ostap Safin, EDM | RW | February 11, 1999 | Praha, Czech Republic |
| Anthony Salinitri, RYK | C | March 5, 1998 | Windsor, Ontario, Canada |
| Saku Salminen, PHI | C | October 20, 1994 | Helsinki, Finland |
| Robin Salo, WHI | D | October 13, 1998 | Espoo, Finland |
| Miikka Salomaki, HAV | LW/RW | March 9, 1993 | Raahe, Finland |
| Dylan Samberg, ACA | D | January 24, 1999 | Hermantown, Minnesota, United States |
| Jordan Sambrook, VAV | D | April 11, 1998 | Markham, Ontario, Canada |
| Dmitri Samorukov, EDM | D | June 16, 1999 | Volgograd, Russia |
| Ilya Samsonov, CZE | G | February 22, 1997 | Magnitogorsk, Russia |
| Jordan Samuels-Thomas, LON | LW | May 28, 1990 | Hartford, Connecticut, United States |
| Henrik Samuelsson, WHI | C/LW/RW | February 7, 1994 | Pittsburgh, Pennsylvania, United States |
| Philip Samuelsson, EDM | D | July 26, 1991 | Leksand, Sweden |
| Carter Sandlak, CHI | LW | May 18, 1993 | Vancouver, British Columbia, Canada |
| Felix Sandstrom, HBG | G | January 12, 1997 | Gavie, Sweden |
| Zachary Sanford, RYK | C/LW/RW | November 9, 1994 | Salem, Massachusetts, United States |
| Travis Sanheim, MTL | D | March 29, 1996 | Elkhorn, Manitoba, Canada |
| Steven Santini, VAN | D | March 7, 1995 | Bronxville, New York, United States |
| Vinny Saponari, STK | RW | February 15, 1990 | Powder, Georgia, United States |
| Charles Sarault, BRN | C | February 20, 1992 | Mississauga, Ontario, Canada |
| Juuse Saros, CZE | G | April 19, 1995 | Forssa, Finland |
| Harri Sateri, EDM | G | December 29, 1989 | Toijala, Finland |
| Ashton Sautner, CHI | D | May 27, 1994 | Flin Flon, Manitoba, Canada |
| David Savard, BOS | D | October 22, 1990 | St. Hyacinthe, Québec, Canada |
| Luca Sbisa, STL | D | January 30, 1990 | Oberageri, Switzerland |
| Marco Scandella, STK | D | February 23, 1990 | Montréal, Québec, Canada |
| Colton Sceviour, STK | LW/RW | April 20, 1989 | Red Deer, Alberta, Canada |
| Tim Schaller, DUB | LW/RW | November 16, 1990 | Merrimack, Hew Hampshire, United States |
| Mark Scheifele, CGY | C | March 15, 1993 | Kitchener, Ontario, Canada |
| Geoffrey Schemitsch, NS | D | April 1, 1992 | Toronto, Ontario, Canada |
| Thomas Schemitsch, HAV | D | October 26, 1996 | Thornhill, Ontario, Canada |
| Brayden Schenn, KC | C/LW/RW | August 22, 1991 | Saskatoon, Saskatchewan, Canada |
| Luke Schenn, VAN | D | February 11, 1989 | Saskatoon, Saskatchewan, Canada |
| Nikita Scherbak, DEN | RW | December 30, 1995 | Moscow, Russia |
| David Schlemko, WHI | D | May 7, 1987 | Edmonton, Alberta, Canada |
| Jordan Schmaltz, CHI | D | October 8, 1993 | Madison, Wisconsin, United States |
| Nick Schmaltz, DEN | C/LW | February 23, 1996 | Madison, Wisconsin, United States |
| Matt Schmalz, STL | C | March 21, 1996 | Dunnville, Ontario, Canada |
| Adam Schmidt, LON | C/LW/RW | November 16, 1990 | Warrington, Pennsylvania, United States |
| Nate Schmidt, OTT | D | July 16, 1991 | St. Cloud, Minnesota, United States |
| Beau Schmitz, LON | D | March 26, 1991 | Howell, Michigan, United States |
| Nate Schnarr, FRE | C | February 25, 1999 | Waterloo, Ontario, Canada |
| Cole Schneider, OTT | LW/RW | August 26, 1990 | Williamsville, New York, United States |
| Cory Schneider, VAV | G | March 18, 1986 | Salem, Massachusetts, United States |
| Nick Schneider, NS | G | July 21, 1997 | Leduc, Alberta, Canada |
| Stefan Schneider, BRN | C | December 13, 1989 | Vernon, British Columbia, Canada |
| Ryan Schnell, CZE | LW | January 13, 1989 | Cary, Illinios, United States |
| Alex Schoenborn, CHI | RW | December 12, 1995 | Minot, North Dakota, United States |
| Jordan Schroeder, STL | C/LW/RW | September 29, 1990 | Burnsville, Minnesota, United States |
| Jeff Schultz, CZE | D | February 25, 1986 | Calgary, Alberta, Canada |
| Justin Schultz, BRN | D | June 7, 1990 | Kelowna, British Columbia, Canada |
| Nick Schultz, BRN | D | August 25, 1982 | Strasbourg, Saskatchewan, Canada |
| Michael Schumacher, OTT | LW | August 25, 1993 | Ornskoldsvik, Sweden |
| Jaden Schwartz, RYK | C/LW | June 25, 1992 | Melfort, Saskatchewan, Canada |
| Ian Scott, EDM | G | January 11, 1999 | Calgary, Alberta, Canada |
| Rob Scuderi, PHI | D | December 30, 1978 | Syosset, New York, United States |
| Brent Seabrook, EDM | D | April 2, 1985 | Delta, British Columbia, Canada |
| Daniel Sedin, HBG | LW | September 26, 1980 | Ornskoldsvik, Sweden |
| Henrik Sedin, TOM | C | September 26, 1980 | Ornskoldsvik, Sweden |
| Lukas Sedlak, MTL | C/LW | February 25, 1993 | Ceske Budejovice, Czech Republic |
| Nick Seeler, STL | D | June 3, 1993 | Eden Prairie, Minnesota, United States |
| Justin Sefton, HBG | D | April 14, 1993 | Thunder Bay, Ontario, Canada |
| Ryan Segalla, HBG | D | December 29, 1994 | Boston, Massachusetts, United States |
| Tyler Seguin, HAV | C/RW | January 31, 1992 | Brampton, Ontario, Canada |
| Dennis Seidenberg, QUE | D | July 18, 1981 | Villingen-Schwenningen, Germany |
| Jiri Sekac, CZE | LW/RW | June 10, 1992 | Kladno, Czech Republic |
| Andrej Sekera, BRN | D | June 8, 1986 | Bojnice, Slovakia |
| Brett Seney, HBG | LW | February 28, 1996 | London, Ontario, Canada |
| Gilles Senn, PHI | G | March 1, 1996 | Buelach, Switzerland |
| Zach Senyshyn, FRE | RW | March 30, 1997 | Ottawa, Ontario, Canada |
| Mikhail Sergachev, BNF | D | June 25, 1998 | Nizhnekamsk, Russia |
| Artem Sergeev, OTT | D | April 20, 1993 | Moscow, Russia |
| Malte Setkov, FRE | D | January 14, 1999 | Rødovre, Denmark |
| Damon Severson, WHI | D | August 7, 1994 | Brandon, Manitoba, Canada |
| Ben Sexton, OTT | C/RW | May 6, 1991 | Ottawa, Ontario, Canada |
| Clark Seymour, DEN | D | May 18, 1993 | Brockville, Ontario, Canada |
| Michael Sgarbossa, NS | C/LW | July 25, 1992 | Campbellville, Ontario, Canada |
| Josh Shalla, KC | LW | September 25, 1991 | Oshawa, Ontario, Canada |
| Maxim Shalunov, RYK | RW | January 31, 1993 | Chelyabinsk, Russia |
| Patrick Sharp, CZE | LW/RW | December 27, 1981 | Thunder Bay, Ontario, Canada |
| Kevin Shattenkirk, STL | D | January 29, 1989 | Greenwich, Conneticut, United States |
| Andrew Shaw, CGY | C/LW/RW | July 20, 1991 | Belleville, Ontario, Canada |
| Logan Shaw, DUB | C/LW/RW | October 5, 1992 | Glace Bay, Nova Scotia, Canada |
| Mason Shaw, NS | C | November 3, 1998 | Lloydminster, Alberta, Canada |
| Ryan Shea, STL | D | February 11, 1997 | Milton, Massachusetts, United States |
| Riley Sheahan, DEN | C/LW | July 12, 1991 | St. Catherines, Ontario, Canada |
| Conor Sheary, FRE | LW/RW | June 8, 1992 | Winchester, Massachusetts, United States |
| Wiley Sherman, HBG | D | May 24, 1995 | Greenwich, Connecticut, United States |
| Igor Shesterkin, KC | G | December 30, 1995 | Moscow, Russia |
| David Shields, VAV | D | January 27, 1991 | Rochester, New York, United States |
| Hunter Shinkaruk, STK | LW/RW | October 13, 1994 | Calgary, Alberta, Canada |
| Brendan Shinnimin, BRN | C | January 7, 1991 | Winnipeg, Manitoba, Canada |
| Devin Shore, ACA | C/LW/RW | July 19, 1994 | Ajax, Ontario, Canada |
| Drew Shore, WHI | C | January 29, 1991 | Denver, Colorado, United States |
| Nicholas Shore, WHI | C | September 26, 1992 | Denver, Colorado, United States |
| Quentin Shore, MTL | C/RW | May 25, 1994 | Denver, Colorado, United States |
| Justin Shugg, BRN | LW/RW | December 24, 1991 | Niagara Falls, Ontario, Canada |
| Igor Shvyrev, BNF | C | July 10, 1998 | Magnitogorsk, Russia |
| Deven Sideroff, DUB | RW | April 14, 1997 | Kamloops, British Columbia, Canada |
| Blake Siebenaler, NS | D | February 27, 1996 | Toledo, Ohio, United States |
| Jonas Siegenthaler, FRE | D | May 6, 1997 | Zurich, Switzerland |
| Patrick Sieloff, KC | D | May 15, 1994 | Ann Arbor, Michigan, United States |
| Duncan Siemens, VAN | D | September 7, 1993 | Edmonton, Alberta, Canada |
| Stephen Silas, LON | D | June 26, 1992 | Brampton, Ontario, Canada |
| Jakob Silfverberg, BOS | LW/RW | October 13, 1991 | Gavle, Sweden |
| Zack Sill, BNF | C/LW | May 24, 1988 | Truro, Nova Scotia, Canada |
| Petteri Simila, VAN | G | April 9, 1990 | Oulu, Finland |
| Wayne Simmonds, LV | RW | August 26, 1988 | Scarborough, Ontario, Canada |
| Dominik Simon, CZE | C/LW/RW | August 8, 1994 | Prague, Czech Republic |
| Frankie Simonelli, CGY | D | October 29, 1992 | Bensenville, Illinois, United States |
| Dillon Simpson, DUB | D | February 10, 1993 | Edmonton, Alberta, Canada |
| Kent Simpson, QUE | G | March 26, 1992 | Edmonton, Alberta, Canada |
| Dmitry Sinitsyn, QUE | D | June 17, 1994 | Moscow, Russia |
| Mike Sislo, TOM | RW | January 20, 1988 | Muurame, Finland |
| Colton Sissons, OTT | C/LW/RW | November 5, 1993 | North Vancouver, British Columbia, Canada |
| Calle Sjalin, NS | D | September 2, 1999 | Ostersund, Sweden |
| MacKenzie Skapski, QUE | G | June 15, 1994 | Abbotsford, British Columbia, Canada |
| Jack Skille, LON | LW/RW | May 19, 1987 | Madison, Wisconsin, United States |
| Jeff Skinner, STL | LW | May 16, 1992 | Markham, Ontario, Canada |
| Stuart Skinner, CZE | G | November 1, 1998 | Edmonton, Alberta, Canada |
| Brady Skjei, VAV | D | March 26, 1994 | Lakeville, Minnesota, United States |
| Jacob Slavin, STL | D | May 1, 1994 | Denver, Colorado, United States |
| Anton Slepyshev, CZE | LW/RW | May 13, 1994 | Penza, Russia |
| Spencer Smallman, MTL | RW | September 9, 1996 | Summerside, Prince Edward Island, Canada |
| Denis Smirnov, LV | RW | August 12, 1997 | Moscow, Russia |
| Ben Smith, BNF | C/RW | July 11, 1988 | Avon, Connecticut, United States |
| Brendan Smith, HBG | D | February 8, 1989 | Toronto, Ontario, Canada |
| Colin Smith, FRE | C/RW | June 20, 1993 | Edmonton, Alberta, Canada |
| Craig Smith, HBG | RW | September 5, 1989 | Madison, Wisconsin, United States |
| Evan Smith, DUB | G | February 27, 1997 | Parker, Colorado, United States |
| Gemel Smith, CGY | C/LW | April 16, 1994 | Toronto, Ontario, Canada |
| Givani Smith, CHI | RW | February 28, 1998 | Thornhill, Ontario, Canada |
| Hunter Smith, WHI | RW | September 11, 1996 | Windsor, Ontario, Canada |
| Jeremy Smith, WHI | G | April 13, 1989 | Dearborn, Michigan, United States |
| Mike Smith, BRN | G | March 22, 1982 | Verona, Ontario, Canada |
| Reilly Smith, FRE | LW/RW | April 1, 1991 | Toronto, Ontario, Canada |
| Zack Smith, KC | C/LW | May 4, 1988 | Medicine, Alberta, Canada |
| Devante Smith-Pelly, STK | LW/RW | June 14, 1992 | Scarborough, Ontario, Canada |
| Luc Snuggerud, MTL | D | September 18, 1995 | Edina, Minnesota, United States |
| Markus Soberg, KC | RW | April 22, 1995 | Oslo, Norway |
| Steffen Soberg, HAV | G | August 6, 1993 | Oslo, Norway |
| Andreas Soderberg, CGY | D | June 16, 1996 | Skelleftea, Sweden |
| Carl Soderberg, DUB | C/LW | October 12, 1985 | Malmo, Sweden |
| Tim Soderlund, VAV | LW | January 23, 1998 | Skellefteå, Sweden |
| Linus Soderstrom, KC | G | August 23, 1996 | Stockholm, Sweden |
| Dmitry Sokolov, HBG | RW | April 14, 1998 | Omsk, Russia |
| Doyle Somerby, STL | D | July 4, 1994 | Marblehead, Massachusetts, United States |
| Otto Somppi, CGY | C | January 12, 1998 | Helsinki, Finland |
| Andong Song, CGY | D | January 31, 1997 | Beijing, China |
| Brett Sonne, STK | C/LW | March 16, 1989 | Chilliwack, British Columbia, Canada |
| Markus Sorensen, CGY | LW/RW | April 7, 1992 | Sodertalje, Sweden |
| Nick Sorensen, TOM | RW | October 23, 1994 | Holback, Denmark |
| Ilya Sorokin, STK | G | August 4, 1995 | Mezhdurechensk, Russia |
| Nikita Soshnikov, TOM | LW/RW | October 14, 1993 | Nizhny Tagil, Russia |
| Oleg Sosunov, CGY | D | April 13, 1998 | Ryazan, Russia |
| Carson Soucy, ACA | D | July 27, 1994 | Viking, Alberta, Canada |
| Tyler Soy, ACA | C | February 10, 1997 | Richmond, British Columbia, Canada |
| Michael Spacek, HAV | RW | April 9, 1997 | Marianske Lazne, Czech Republic |
| Garret Sparks, HAV | G | June 28, 1993 | Elmhurst, Illinois, United States |
| Blake Speers, HAV | C | January 2, 1997 | Sault Ste. Marie, Ontario, Canada |
| Thomas Spelling, STK | LW/RW | February 9, 1993 | Herning, Denmark |
| Matthew Spencer, DEN | D | March 24, 1997 | Guelph, Ontario, Canada |
| Jason Spezza, KC | C/RW | June 13, 1983 | Mississauga, Ontario, Canada |
| Steven Spinner, BNF | RW | December 15, 1995 | Eden Prairie, Minnesota, United States |
| Ryan Spooner, HAV | C/LW | January 30, 1992 | Ottawa, Ontario, Canada |
| Daniel Sprong, BOS | RW | March 17, 1997 | Amsterdam, Netherlands |
| Ryan Sproul, TOM | D | January 13, 1993 | Mississauga, Ontario, Canada |
| Jared Spurgeon, FRE | D | November 29, 1989 | Edmonton, Alberta, Canada |
| Michael St. Croix, QUE | C | April 10, 1993 | Winnipeg, Manitoba, Canada |
| Eric Staal, STK | C/LW | October 29, 1984 | Thunder Bay, Ontario, Canada |
| Jordan Staal, WHI | C | September 10, 1988 | Thunder Bay, Ontario, Canada |
| Marc Staal, CHI | D | January 13, 1987 | Thunder Bay, Ontario, Canada |
| Drew Stafford, DUB | LW/RW | October 30, 1985 | Milwaukee, Wisconsin, United States |
| Matthew Stajan, STL | C/LW | December 19, 1983 | Mississauga, Ontario, Canada |
| Scott Stajcer, QUE | G | July 14, 1991 | Cambridge, Ontario, Canada |
| Viktor Stalberg, EDM | LW/RW | January 17, 1986 | Stockholm, Sweden |
| Jordy Stallard, RYK | C | September 18, 1997 | Brandon, Manitoba, Canada |
| Alex Stalock, QUE | G | July 28, 1987 | St. Paul, Minnesota, United States |
| Steven Stamkos, PHI | C/RW | July 2, 1990 | Markham, Ontario, Canada |
| Logan Stanley, TOM | D | May 26, 1998 | Waterloo, Ontario, Canada |
| Ryan Stanton, CHI | D | July 20, 1989 | St. Albert, Alberta, Canada |
| Beau Starrett, HBG | LW/RW | November 1, 1995 | Framingham, Massachusetts, United States |
| Paul Stastny, DEN | C | December 27, 1985 | St. Louis, Missouri, United States |
| Casey Staum, DEN | D | January 8, 1998 | Roseville, Minnesota, United States |
| Sam Steel, HAV | C | February 3, 1998 | Ardrossan, Alberta, Canada |
| Alexander Steen, DUB | C/LW/RW | March 1, 1984 | Winnipeg, Manitoba, Canada |
| Oskar Steen, LON | C | March 9, 1998 | Karlstad, Sweden |
| Tyler Steenbergen, DUB | C | January 7, 1998 | Sylvan Lake, Alberta, Canada |
| Taylor Stefishen, STK | LW | August 15, 1990 | Vancouver, British Columbia, Canada |
| Lee Stempniak, MTL | RW | February 4, 1983 | West Seneca, New York, United States |
| Kevin Stenlund, VAV | C | September 20, 1996 | Huddinge, Sweden |
| Derek Stepan, RYK | C | June 18, 1990 | Hastings, Minnesota, United States |
| Zachary Stepan, HAV | C | January 6, 1994 | Hastings, Minnesota, United States |
| Devante Stephens, WHI | D | January 2, 1997 | Surrey, British Columbia, Canada |
| Mitchell Stephens, STK | C | February 5, 1997 | Peterborough, Ontario, Canada |
| Chandler Stephenson, FRE | C | April 22, 1994 | Saskatoon, Saskatchewan, Canada |
| Luke Stevens, CZE | LW | February 11, 1997 | Bellair, California, United States |
| Nolan Stevens, KC | C | July 22, 1996 | Brantford, Ontario, Canada |
| Dustin Stevenson, CHI | D | August 12, 1989 | Gull Lake, Saskatchewan, Canada |
| Chris Stewart, EDM | LW/RW | October 30, 1987 | Toronto, Ontario, Canada |
| Dean Stewart, WHI | D | June 12, 1998 | Portage, Manitoba, Canada |
| Ales Stezka, HBG | G | January 6, 1997 | Liberec, Czech Republic |
| Riley Stillman, HAV | D | March 9, 1998 | Peterborough, Ontario, Canada |
| Anthony Stolarz, ACA | G | January 20, 1994 | Edison, New Jersey, United States |
| Karl Stollery, DUB | D | November 21, 1987 | Camrose, Alberta, Canada |
| Mark Stone, WHI | RW | May 13, 1992 | Winnipeg, Manitoba, Canada |
| Michael Stone, WHI | D | July 6, 1990 | Winnipeg, Manitoba, Canada |
| Clayton Stoner, NS | D | February 19, 1985 | Port McNeill, British Columbia, Canada |
| Zach Stortini, BRN | RW | September 11, 1985 | Elliot Lake, Ontario, Canada |
| Tyson Strachan, TOM | D | October 30, 1984 | Melfort, Saskatchewan, Canada |
| Brian Strait, HBG | D | January 4, 1988 | Boston, Massachusetts, United States |
| Petr Straka, PHI | LW/RW | June 15, 1992 | Plzen, Czech Republic |
| Anton Stralman, LV | D | August 1, 1986 | Tibro, Sweden |
| Matej Stransky, MTL | RW | July 11, 1993 | Ostrava, Czech Republic |
| Ben Street, TOM | C | February 13, 1987 | Coquitlam, British Columbia, Canada |
| Mark Streit, DUB | D | December 11, 1977 | Englisberg, Switzerland |
| Dylan Strome, STK | C | March 7, 1997 | Mississauga, Ontario, Canada |
| Matthew Strome, STK | LW | January 6, 1999 | Mississauga, Ontario, Canada |
| Ryan Strome, HBG | C/RW | July 11, 1993 | Mississauga, Ontario, Canada |
| Mark Stuart, CGY | D | April 27, 1984 | Rochester, Minnesota, United States |
| Marian Studenic, VAV | RW | October 28, 1998 | Skalica, Slovakia |
| Jack Studnicka, FRE | C | February 18, 1999 | Windsor, Ontario, Canada |
| Jakob Stukel, ACA | LW | March 6, 1997 | Vancouver, British Columbia, Canada |
| Jordan Subban, WHI | D | March 3, 1995 | Toronto, Ontario, Canada |
| Malcolm Subban, WHI | G | December 21, 1993 | Toronto, Ontario, Canada |
| P.K. Subban, LV | D | May 13, 1989 | Toronto, Ontario, Canada |
| Colin Suellentrop, STK | D | June 10, 1993 | Plantation, Florida, United States |
| Chris Summers, KC | D | February 5, 1988 | Ann Arbor, Michigan, United States |
| Kelly Summers, MTL | D | April 29, 1996 | Renfrew, Ontario, Canada |
| Kevin Sundher, LON | C | January 18, 1992 | Surrey, British Columbia, Canada |
| Oskar Sundqvist, DEN | C | March 23, 1994 | Boden, Sweden |
| Johan Sundstrom, STK | C | September 21, 1992 | Gothenburg, Sweden |
| Maksim Sushko, STK | RW | February 10, 1999 | Brest, Belarus |
| Andrej Sustr, KC | D | November 29, 1990 | Plzen, Czech Republic |
| Ryan Suter, QUE | D | January 21, 1985 | Madison, Wisconsin, United States |
| Brandon Sutter, BRN | C/RW | February 14, 1989 | Red Deer, Alberta, Canada |
| Brett Sutter, BRN | C/LW | June 2, 1987 | Viking, Alberta, Canada |
| Brody Sutter, EDM | C | September 26, 1991 | Viking, Alberta, Canada |
| Lukas Sutter, CZE | C | October 4, 1993 | St. Louis, Missouri, United States |
| Nick Suzuki, BNF | C | August 10, 1999 | London, Ontario, Canada |
| Evgeny Svechnikov, MTL | LW/RW | October 31, 1996 | Yuzhno-Sakhalinsk, Russia |
| Niklas Svedberg, CZE | G | September 4, 1989 | Sollentuna, Sweden |
| Viktor Svedberg, OTT | D | May 24, 1991 | Gothenborg, Sweden |
| Jeremy Swayman, HBG | G | November 24, 1998 | Anchorage, Alaska, United States |
| Jordan Szwarz, BRN | RW | May 14, 1991 | Burlington, Ontario, Canada |